6RELEASE
Solubility Secrets: From Stomach to Intestine, Where Does Absorption Peak?
2 min read
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Essentials
- The body requires efficient digestion and absorption of both macronutrients (carbohydrates, proteins, fats) for energy and micronutrients (vitamins, minerals) for metabolic support, with the performance of micronutrients heavily dependent on their absorption.*
- Digestion begins in the mouth and continues in the stomach where enzymes and hydrochloric acid break down food, but the rate of digestion varies among different nutrient types, influencing the design of targeted nutrient delivery technologies.
Nutrition isn't just about eating right... it's also about nutrient absorption. Because nutrients, whether obtained from food or nootropics, aren't truly part of your organism until absorbed. Before that, they are merely in transit.
In other words, optimizing your nutrition requires more than worrying about what you eat. You also need to get a handle on what happens to nutrients once they're down the hatch. Why? It's simple: poor nutrient absorption may lead to a number of health issues, including anemia, attention challenges, brain fog, or low energy, just to name a few.*1
Optimizing your body's nutritional absorption can significantly lower the risks associated with nutritional deficiencies.*
Your body absorbs two types of nutrients: macronutrients and micronutrients.
- Macronutrients (like carbohydrates, proteins, and fats) are your primary energy sources.
- On the other hand, micronutrients (the vitamins and minerals) typically play a 'supporting' role by helping release energy from macronutrients. Yet, their effectiveness is contingent on efficient absorption, or none of these nutrients can fulfill their duties... at least not as they should.*
Digestion is where nutrient absorption begins.
After food is chewed and broken down by enzymes in your saliva, it moves down to the stomach. Here, the digestive process is amplified by hydrochloric acid and enzymes such as protease (for proteins), lipase (for fats), and amylase (for carbohydrates).2
Now, here's something you may not know: certain nutrients, like fats and proteins, take longer to be digested compared to, let's say, carbohydrates. That can happen because carb-digesting enzymes are activated earlier in the process. Why does this matter?
Because this 'tiny detail' helped us develop our nutrient delivery and time-release technology: designed to release nutrients where absorption peaks.*
The human stomach's acidic pH (1.5 - 3.5) primarily breaks down food, especially proteins. But, although the stomach is a hotbed of digestive processes, it's not where absorption predominantly occurs.
That role is reserved for the small intestine (where the pH is 7.4 - it becomes mildly alkaline), which absorbs proteins, carbohydrates, fats, water, vitamins, and minerals.
That's why our HCF® nootropics use a technology based on microbeads—tiny spheres—that help select nutrients bypass the stomach's acidity and dissolve in the small intestine, where absorption is optimal. This protective coating can also improve the nutrient absorption rate in the alkaline environment, maximizing the effectiveness of each nutrient.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The contents of this website do not constitute advice and are provided for informational purposes only. See our full medical disclaimer
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Meet Our Experts

Conor Sheehy PharmD, BCPS, CACP
Author, Linkedin
Author, Linkedin
Dr. Sheehy earned a BS in Molecular Biology from the University of Idaho and a Doctor of Pharmacy (PharmD) from the University of Washington. He is a Board-Certified Pharmacotherapy Specialist (BCPS) and a Certified Anticoagulation Care Provider (CACP). As a member of the American Medical Writers Association, the College of Psychiatric and Neurological Pharmacists (CPNP), and the National Alliance on Mental Illness (NAMI), his focus has been on innovative dosage deliverability strategies that primarily benefit individuals facing mental health challenges.