6RELEASE
Dimensions of Delivery: Balancing Microbead Size & Release Profiles
3 min read
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Essentials
- The surface area-to-volume ratio of microbeads influences the rate at which nootropics are released, with smaller microbeads releasing nutrients faster due to a higher surface area.*
- Achieving the right balance in nootropic formulation helps prevent issues like overstimulation or insufficient effectiveness, ensuring a steady and safe supply of cognitive enhancement.*
Many brands cleverly use tiny, colorful spheres inside transparent capsules to catch your eye. These spheres, known as microbeads, certainly do grab attention. People love the look.
But here's a lesser-known fact that's quite important to the effectiveness of nootropics (and it often flies under the radar): these little spheres do more than just look good. They can play a significant role in how nutrients are released into your body.*
In fact, microbeads' size can significantly influence their release properties, striking a delicate balance between size, dosage, and release profile.*
Feeling a bit lost?
No worries—you're in good company. Let us explain how the size of these microbeads can make a noticeable difference in how your favorite nootropic performs.*
Why do we use specific sizes for our microbeads?
Glad you asked. :-)
The size of a microbead affects its surface area-to-volume ratio. And why is this ratio so important? Because it influences how quickly the nootropic is released into your body.*1
Here's a simpler way to look at it: smaller microbeads have a higher surface area compared to their volume. What does this mean for you? A quicker release rate, since there's more surface for the body's digestive fluids to work on.*
On the flip side, larger microbeads, with less surface area relative to their volume, release their nutrients more gradually.*
In essence, by choosing specific microbead sizes, it helps us control how fast or slow the nootropics are released. It's a key strategy for nootropics to work as intended, providing the desired effects over the right time frame.*
But...balancing the dosage and release profile is critical
The interplay between microbead size, dosage, and release profile is complex.
For example: you face a critical deadline for a project or presentation. A nootropic could be just what you need to stay sharp, focused, and productive.*
And if the microbeads inside the capsule are tiny, they're likely designed to release their active nutrients quickly, giving you an immediate boost. However, you may need to take additional doses to maintain that heightened focus throughout the day.*2
This is where the balance comes in:
→ Take too much, and you could end up with unwanted side effects, like feeling jittery or experiencing a crash later.*3
→ Take too little, and you might not feel any benefit at all. Neither scenario is ideal.*3
But now, if those microbeads inside are larger, they can slowly release their nutrients over time. This could mean that just one dose in the morning is enough to keep you dialed in all day long.*2
However, the trick is to strike the right balance. You don't want the release to be so slow that it doesn't provide enough of a boost when you need it, nor so fast that it leads to overstimulation or other harmful effects.*
That's where the art of balancing—finding the optimal size and number of microbeads for a gradual, effective release—comes in. This way, your body gets a steady supply of the good stuff without the risk of taking too much at once.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The contents of this website do not constitute advice and are provided for informational purposes only. See our full medical disclaimer
Sources
Meet Our Experts

Conor Sheehy PharmD, BCPS, CACP
Author, Linkedin
Author, Linkedin
Dr. Sheehy earned a BS in Molecular Biology from the University of Idaho and a Doctor of Pharmacy (PharmD) from the University of Washington. He is a Board-Certified Pharmacotherapy Specialist (BCPS) and a Certified Anticoagulation Care Provider (CACP). As a member of the American Medical Writers Association, the College of Psychiatric and Neurological Pharmacists (CPNP), and the National Alliance on Mental Illness (NAMI), his focus has been on innovative dosage deliverability strategies that primarily benefit individuals facing mental health challenges.