The Differences in Digestion: Gelatin vs. Vegan Capsules

Thinking about taking a nootropic for the first time? Or perhaps you're looking for one that better suits your current needs? Choosing a nootropic can be challenging—which isn't surprising considering the brain's complexity.

But beyond nutrients and claims, there are a few extra details you may want to consider when browsing for a nootropic.

Knowing the differences between Gelatin and vegan capsules may seem unimportant—but it can make a big difference.

Let's explain. Gelatin capsules (typically made from animal collagen) may not be suitable for vegans, vegetarians, or those with dietary restrictions. However, vegetarian capsules made from plant-based cellulose can be.¹ And that's just one aspect.*

Here's what else you may want to consider:

Why is Gelatin used in capsules?

Gelatin capsules are available in both hard and soft forms and are quite popular in the nootropic industry primarily due to their lower production costs. Simply put, they are considerably cheaper to manufacture.

But just because they are cheaper doesn't mean they can't bring something to the table (sort of).

For instance, due to their low moisture content (3%—7%), Gelatin capsules typically have a longer shelf life and can better maintain the potency of the active nutrients.⁴ Plus, they dissolve well at body temperature (37°C), so the nutrients can be released and absorbed more efficiently.*

However, it's worth noting that Gelatin capsules can experience cross-linking. This process can reduce their solubility, particularly when exposed to certain substances or environmental factors like high humidity and UV light.*

Vegan capsules can be an alternative for those interested in a non-animal option.

Typically made from Hydroxypropyl Methylcellulose (HPMC)—a plant-derived component—vegetarian capsules come with their own perks (especially in improving the bioavailability and solubility of poorly absorbed nutrients).*

Ongoing research suggests that vegan capsules can create a more stable environment for nutrients, helping prevent them from forming crystals (that your body may struggle to absorb well) in the gastrointestinal (GI) tract.*^5,6

Plus, because they are derived from cellulose—a natural polymer found in plant cell walls—they avoid the animal proteins that can sometimes trigger allergic reactions.*

And finally, vegan capsules also tend to be gentler on the stomach than Gelatin capsules. Gelatin can sometimes cause digestive discomfort or irritation (in sensitive individuals). On the other hand, vegan capsules are less likely to cause such challenges because they are more inert and hypoallergenic.*

This can be particularly important for individuals who have a history of digestive issues or those who take nootropics on an empty stomach.*

The choice is yours.

Both Gelatin and vegan capsules have their advantages, and the choice can largely depend on your preferences. If dietary restrictions and religious beliefs are not a concern, Gelatin capsules may be preferred due to their lower cost.

On the other hand, if you prioritize stability and solubility and have concerns about animal products, you can opt for vegan capsules.

At HCF®, we choose HPMC compact Size 0 / 0EL Gellan Gum capsules for our advanced nootropics. Gellan Gum capsules align better with our 7 Advances® and clean label principles for purity, transparency, & safety you can trust.