1NUTRIENTS
L-Theanine & Your Brain
6 min read

Essentials
- The calming vibe from sipping green or black tea is due to L-Theanine, an amino acid found naturally in tea and some mushrooms, known for its potent cognitive health and mental load management benefits.*
- L-Theanine is well-absorbed in the gut and can cross the blood-brain barrier, increasing relaxing neurochemicals and reducing stimulating ones, thus balancing mood and enhancing cognitive function.*
Do you know that calming vibe you get from sipping green or black tea? Well, that's thanks to L-Theanine.
L-Theanine is not just an amino acid found naturally in green tea, black tea, and some mushrooms. According to science, it may also be one of the most potent cognitive health and mental load management nutrients.* And let's face it. We all have to deal with a lot of tension and pressure nowadays.
Now, the real issue with mental load is that even occasional anxiousness can negatively impact cognitive function and cause difficulty with information processing, focus, and memory.*
In addition, as we age, we are more likely to experience changes in memory and focus. If you are one of the many who struggle with anxiousness, brain fog, or memory challenges, you may benefit from L-Theanine.*1
But how exactly does it work? And why you shouldn't skip on your L-Theanine intake.
L-Theanine may keep your head-brain happy, calm, and focused.*
L-Theanine is well absorbed in the small intestine (part of your gut-brain system). Plus, unlike some other nutrients, it can zip through the blood-brain barrier (BBB).*
According to research, once it reaches your ‘Mental Intelligence Center’ (the head-brain), this amino acid may increase relaxing neurochemicals (like GABA, serotonin, and dopamine) and reduce stimulating ones.2 It's a win-win situation. Why? Because all these neurotransmitters may be necessary to maintain a balanced mood, regulate emotions, and ensure optimal cognitive function.*
Take GABA, for instance. It can act as the brain's primary inhibitory neurotransmitter.
What does that mean? Well, it's a complex chemical process, but, in short, GABA can help your Central Nervous System (CNS) not become overactive.*3
On the other hand, serotonin, often termed the 'feel-good neurotransmitter,' can help regulate mood, happiness, and anxiousness. And finally, dopamine is all about pleasure, attention, and mood.*
L-Theanine may protect your neurons.*
Now, here's something you may not be aware of: cognitive health isn't just about neurotransmitters. It's also about the physical well-being of each individual brain cell (neuron).
Luckily, according to studies, L-Theanine may play an important role in this, too. How? By modulating various signaling pathways, which, in turn, helps your neurons communicate more efficiently.*
But more importantly, it may reduce oxidative stress, a primary culprit responsible for cell damage.*
May boost the overall cognitive function.*
Feeling the pressure? The uneasiness? The constant mental load?
Here's what may have happened: When frazzled, your body may pump out stress hormones—like cortisol. The downside? These hormones can muddle up your head-brain's usual groove, making it difficult to focus or remember things.
But L-Theanine's ability to balance stress hormones may just give it the potential to enhance cognitive function. And there's plenty of proof to back this up.*
Another study on 32 healthy young adults found that doses of L-Theanine, anywhere from 100 to 400 mg, significantly amped up their attention and info-processing skills compared to those who received a placebo.*4
L-Theanine also seems to have a more significant attention-boosting effect when taken by people predisposed to high feelings of anxiousness. This suggests that those with occasional exposure to stress hormones could significantly benefit from supplementing with L-Theanine.*5
Issues with falling or staying asleep? L-Theanine might offer a solution.*
While not a sedative, its calming effects can help combat night-time wakefulness and improve overall sleep quality.6 By regulating neurotransmitters linked to mood changes and tension, it can create an environment conducive to restful sleep. Rest better. Think clearer.*
Why some HCF® nootropics bank on both L-Theanine and L-Glutamine.
At first glance, Glutamine and L-Theanine share structural similarities. Both interact with Glutamate receptors in the brain. So, why use both?
The answer lies in their complementary actions: While Glutamine can offer a steady supply of Glutamate for essential cognitive functions, L-Theanine can modulate its activity, helping reduce potential overexcitation.*
It's a dual approach that may ensure that your brain system has enough Glutamate for cognitive processes while protecting it from excess Glutamate activity risks.*
Can I get enough L-Theanine from diet alone?
You can, but it's quite challenging to do so (unless you follow a strict diet that includes plenty of natural sources of this neuro-nutrient). But the sad truth is this: many don't get enough of this amino acid.*
Why supplementation is often necessary (and sometimes preferred).*
Feeding your brain system with L-Theanine can be one of the best things you can do for your overall cognitive health. But L-Theanine is scarce if you try to get enough of it from foods alone.*
Plus, supplementation may actually be an easier approach for some. Here's why:
Concentration.
The amount of L-Theanine in natural sources, especially compared to the doses used in scientific studies, can be relatively low. For instance, a cup of green tea might contain anywhere from 20-60 mg of L-Theanine, while many studies looking into its potential cognitive benefits use doses ranging from 100-200 mg.*
Consistency.
The L-Theanine content can vary based on factors like the type of tea, its quality, and how it's brewed. On the other hand, a quality nootropic can offer a more consistent dose.*
Purity.
HCF® provides L-Theanine in its pure form, free from other compounds, such as caffeine (abundant in green and black tea). This way you can experience the beneficial effects of L-Theanine without the risk of potential side effects caused by other unwanted substances.*
Hassle-free.
While tea popularity in the United States has increased over the past decade, according to statistics, only about 50% of Americans drink tea daily.7 And for those who don't consume tea regularly, nootropics may offer a hassle-free way to supplement their L-Theanine intake.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The contents of this website do not constitute advice and are provided for informational purposes only. See our full medical disclaimer
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Meet Our Experts

Kerri Rachelle PhD c., RDN, LDN, CSSD, A-CFMP
Author, Linkedin
Author, Linkedin
Kerri Rachelle, a Registered Dietitian (RDN, LDN, CSSD, A-CFMP), PhD candidate in Integrative Medicine, and published author, specializes in nutrient absorption, cellular health, gut health, detoxification, and mental health. She is an international presenter for the Integrative and Functional Nutrition Specialist Certificate Program and the founder of Revolution Health, where she leads a team dedicated to sharing her expertise in natural practices that address the root causes of health issues, empowering health professionals worldwide.