1NUTRIENTS
Active, Accessible, Efficient Vitamin B: The Triple Gold Standard of High Bioactivity 5-Phosphate Coenzymes
3 min read

Essentials
- Genetic factors can hinder the efficient conversion of B vitamins, making their absorption challenging for some individuals.*
- Coenzymated B vitamins are important because they bypass the energy-intensive conversion process in the liver, making them immediately available for use.*
B vitamins. These important nutrients are needed for metabolizing carbohydrates, fats, and proteins into energy and aiding in red blood cell formation. They are also required for normal growth, proper brain function, cardiovascular health, and protein synthesis.*1
But what you may not know is that many may struggle with poor B vitamin absorption due to genetic factors.*2,3
Potential challenges in B vitamin absorption?
Here's the catch. B vitamins are water-soluble. That means they don't stay long in your body. So, you need to consume them on a daily basis.
Not only that, but the liver, your body's 'detox machine,' must also step in and convert these nutrients into their active, coenzymated forms before your body can use them.*
But there’s a twist: this conversion can be quite inefficient. And even more so for those lacking the genetic predisposition to absorb standard B vitamins.1 More often than not, these vitamins can exit your system quickly, before the liver even gets the chance to do its magic.*
So, what's the solution?
Here's a question for you: How can you make sure these important nutrients are properly absorbed and used, not immediately excreted? The answer? High bioactivity 5-phosphate coenzymated B vitamins. That’s what we, at HCF®, use in our advanced nootropics.*
Our approach at HCF® is to use these activated coenzyme forms of B vitamins. Rather than relying on isolated, artificial versions of B complex vitamins that aren't found in nature, we opt for the activated coenzyme forms.
While these vitamins are still produced artificially (in lab conditions), they are scientifically designed to mimic (resemble) natural forms.*
Do you really need coenzymated B vitamins?
"Coenzymated B vitamins." A head-scratching concept for many. But why are they so important?
Well, as mentioned above, B vitamins undergo a conversion in the liver to become biologically active. This conversion requires a lot of metabolic energy. It can be a draining process, especially for seniors or those with certain nutritional deficiencies. In fact, for many, the process can be downright inefficient.*
(!) This inefficiency can lead to a reduced uptake of these important nutrients, potentially leaving them deficient despite consumption.*4
On the other hand, high bioactivity 5-phosphate coenzymes are B vitamins that have already undergone this transformation, making them readily available for the body to use. No waiting, no energy-draining conversion. Just better, more efficient nourishment.*
The ‘Triple Gold Standard’: active, accessible, efficient.*
‘Triple Gold Standard’ might sound like an accolade reserved for Olympic athletes. HCF® aims for three main qualities in our B vitamins: activity, accessibility, and efficiency:*
→ Active: This refers to the nutrient's bioactivity. An active B vitamin is in its prime form, ready to be utilized by the body without further conversions.*
→ Accessible: Accessibility is all about how readily the body can absorb and use the vitamin. It's not just about intake; it's about effective uptake. Coenzymated B vitamins, for instance, bypass the usual metabolic processes, making them instantly available for the body's needs.*
→ Efficient: Efficiency is the pinnacle of the 'Triple Gold Standard.' It's the assurance that the vitamin enters the body and does its job effectively and swiftly.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The contents of this website do not constitute advice and are provided for informational purposes only. See our full medical disclaimer
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Meet Our Experts

Kerri Rachelle PhD c., RDN, LDN, CSSD, A-CFMP
Author, Linkedin
Author, Linkedin
Kerri Rachelle, a Registered Dietitian (RDN, LDN, CSSD, A-CFMP), PhD candidate in Integrative Medicine, and published author, specializes in nutrient absorption, cellular health, gut health, detoxification, and mental health. She is an international presenter for the Integrative and Functional Nutrition Specialist Certificate Program and the founder of Revolution Health, where she leads a team dedicated to sharing her expertise in natural practices that address the root causes of health issues, empowering health professionals worldwide.